USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: CBR1_HUMAN USC-OGP 2-DE database:  CBR1_HUMAN CBR1_HUMAN General information about the entry View entry in simple text format Entry name CBR1_HUMAN Primary accession number P16152 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Carbonyl reductase [NADPH] 1; EC=1.1.1.184; AltName: Full=15-hydroxyprostaglandin dehydrogenase [NADP(+)]; EC=1.1.1.197; AltName: Full=NADPH-dependent carbonyl reductase 1; AltName: Full=Prostaglandin 9-ketoreductase; AltName: Full=Prostaglandin-E(2) 9-reductase; EC=1.1.1.189; AltName: Full=Short chain dehydrogenase/reductase family 21C member 1;. Gene name Name=CBR1 Synonyms=CBR, CRN, SDR21C1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1264: pI=8.37; Mw=29694 Cross-references UniProtKB/Swiss-Prot P16152; CBR1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CBR1_HUMAN Primary accession number P16152 Secondary accession number(s) B2RBZ7 B4DFK7 Q3LHW8 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 188) Name and origin of the protein Description RecName: Full=Carbonyl reductase [NADPH] 1; EC=1.1.1.184; AltName: Full=15-hydroxyprostaglandin dehydrogenase [NADP(+)]; EC=1.1.1.197; AltName: Full=NADPH-dependent carbonyl reductase 1; AltName: Full=Prostaglandin 9-ketoreductase; AltName: Full=Prostaglandin-E(2) 9-reductase; EC=1.1.1.189; AltName: Full=Short chain dehydrogenase/reductase family 21C member 1; Gene name Name=CBR1 Synonyms=CBR, CRN, SDR21C1 Encoded on Name=CBR1; Synonyms=CBR, CRN, SDR21C1 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; NADP; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J04056; AAA52070.1; -; mRNA EMBL M62420; AAA17881.1; -; Genomic_DNA EMBL AB003151; BAA33498.1; -; Genomic_DNA EMBL AP000688; BAA89424.1; -; Genomic_DNA EMBL AB124848; BAE45940.1; -; mRNA EMBL BT019843; AAV38646.1; -; mRNA EMBL CR541708; CAG46509.1; -; mRNA EMBL AK294142; BAG57468.1; -; mRNA EMBL AK314879; BAG37394.1; -; mRNA EMBL EF141836; ABK97430.1; -; Genomic_DNA EMBL AP001724; BAA95508.1; -; Genomic_DNA EMBL CH471079; EAX09754.1; -; Genomic_DNA EMBL CH471079; EAX09755.1; -; Genomic_DNA EMBL BC002511; AAH02511.1; -; mRNA EMBL BC015640; AAH15640.1; -; mRNA CCDS CCDS13641.1; -. [P16152-1]; . CCDS CCDS68202.1; -. [P16152-2]; . PIR A61271; RDHUCB; . RefSeq NP_001273718.1; NM_001286789.1. [P16152-2]; . RefSeq NP_001748.1; NM_001757.3. [P16152-1]; . UniGene Hs.88778; -; . PDB 1WMA; X-ray; 1.24 A; A=2-277 PDB 2PFG; X-ray; 1.54 A; A=2-277 PDB 3BHI; X-ray; 2.27 A; A=2-277 PDB 3BHJ; X-ray; 1.77 A; A=2-277 PDB 3BHM; X-ray; 1.80 A; A=2-277 PDB 4Z3D; X-ray; 1.80 A; A/B/C/D=2-277 PDBsum 1WMA; -; . PDBsum 2PFG; -; . PDBsum 3BHI; -; . PDBsum 3BHJ; -; . PDBsum 3BHM; -; . PDBsum 4Z3D; -; . ProteinModelPortal P16152; -; . SMR P16152; -; . BioGrid 107319; 37; . DIP DIP-33136N; -; . IntAct P16152; 26; . MINT MINT-1418935; -; . STRING 9606.ENSP00000290349; -; . BindingDB P16152; -; . ChEMBL CHEMBL5586; -; . DrugBank DB00414; Acetohexamide; . DrugBank DB00997; Doxorubicin; . DrugBank DB00502; Haloperidol; . DrugBank DB01046; Lubiprostone; . DrugBank DB05197; Sofalcone; . DrugBank DB04844; Tetrabenazine; . GuidetoPHARMACOLOGY 1383; -; . iPTMnet P16152; -; . PhosphoSitePlus P16152; -; . SwissPalm P16152; -; . BioMuta CBR1; -; . DMDM 118519; -; . REPRODUCTION-2DPAGE IPI00295386; -; . UCD-2DPAGE P16152; -; . EPD P16152; -; . MaxQB P16152; -; . PaxDb P16152; -; . PeptideAtlas P16152; -; . PRIDE P16152; -; . TopDownProteomics P16152-1; -. [P16152-1]; . DNASU 873; -; . Ensembl ENST00000290349; ENSP00000290349; ENSG00000159228. [P16152-1]; . Ensembl ENST00000530908; ENSP00000434613; ENSG00000159228. [P16152-2]; . GeneID 873; -; . KEGG hsa:873; -; . UCSC uc002yvb.3; human. [P16152-1]; . CTD 873; -; . DisGeNET 873; -; . GeneCards CBR1; -; . HGNC HGNC:1548; CBR1; . HPA HPA018433; -; . MalaCards CBR1; -; . MIM 114830; gene; . neXtProt NX_P16152; -; . OpenTargets ENSG00000159228; -; . PharmGKB PA26121; -; . eggNOG KOG1208; Eukaryota; . eggNOG COG1028; LUCA; . GeneTree ENSGT00510000046499; -; . HOVERGEN HBG001909; -; . InParanoid P16152; -; . KO K00079; -; . OMA FRSEIIT; -; . OrthoDB EOG091G0V7L; -; . PhylomeDB P16152; -; . TreeFam TF329359; -; . BRENDA 1.1.1.184; 2681; . Reactome R-HSA-2162123; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); . SABIO-RK P16152; -; . EvolutionaryTrace P16152; -; . GeneWiki CBR1; -; . GenomeRNAi 873; -; . PRO PR:P16152; -; . Proteomes UP000005640; Chromosome 21; . Bgee ENSG00000159228; -; . CleanEx HS_CBR1; -; . ExpressionAtlas P16152; baseline and differential; . Genevisible P16152; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:1903561; C:extracellular vesicle; IDA:UniProtKB; . GO GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:UniProtKB-EC; . GO GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB; . GO GO:0016655; F:oxidoreductase activity; acting on NAD(P)H; quinone or similar compound as acceptor IDA:UniProtKB . GO GO:0050221; F:prostaglandin-E2 9-reductase activity; TAS:Reactome; . GO GO:0019371; P:cyclooxygenase pathway; TAS:Reactome; . GO GO:0017144; P:drug metabolic process; IDA:UniProtKB; . GO GO:0030855; P:epithelial cell differentiation; IEP:UniProtKB; . GO GO:0055114; P:oxidation-reduction process; IDA:UniProtKB; . GO GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB; . Gene3D 3.40.50.720; -; 1; . InterPro IPR016040; NAD(P)-bd_dom; . InterPro IPR020904; Sc_DH/Rdtase_CS; . InterPro IPR002347; SDR_fam; . Pfam PF00106; adh_short; 1; . PRINTS PR00081; GDHRDH; . PRINTS PR00080; SDRFAMILY; . SUPFAM SSF51735; SSF51735; 1; . PROSITE PS00061; ADH_SHORT; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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